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Klozapin (LEPONEX)

Da li LEPONEX Uspavljuje.

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#1 Sendy

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Posted 21 May 2006 - 12:10

aKO IKO ZNA MALO VISE O OVOM LEKU,NEKA MI JAVI...POSTO SAM IZGLEDA POSTALA GLAVNO ZAMORCE OVDE GDE ISPROBAVAJU RAZNE LEKICE NA MENI!

#2 MesijaDepresija

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Posted 21 May 2006 - 13:00

Nemoj tako, Sendy. Ako ne radi jedna vrsta terapije, pa makar bila ona i klasicna, ne mora da znaci da ne treba probati i neku novu...

A posto ides da se lecis kod privatnika po tvojoj pisaniji, onda je i logicno da je mogucnost izbora lekova siri nego da ides kod drzavnih lekara...

Ko zna? Mozda je ovo upravo lek koji ce ti pomoci...

Ali i dalje, treba da apstiniras od droge i alkohola koliko je to moguce... Najbolje uvek. Jer u suprotnom ne mozes ocekivati da izadjes zdrava iz svega ovoga. A i ako izadjes. Ako ne prestanes, uvek ces imati jos jedan problem vise - narkomaniju ili alkoholizam. Ne zna se sta je gore... Cak i da ti bude dobro - i da se povremeno samo drogiras ili pijes, bices samo "zalecena" - NIKAKO (I) IZLECENA.

Zato pamet u glavu... Znas sta ti je raditi...

Apstinencija (i) glavu cuva... :meda:

#3 una

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Posted 23 May 2006 - 08:59

Za one, koje ovaj lijek zanima. Informacije sam nasla na netu.

Clozapine (Systemic)
Some commonly used brand names are:

In the U.S.—
Clozaril
In Canada—
Clozaril
Leponex Generic name product may be available in the U.S.

Antipsychotic
Clozapine (KLOE-za-peen) is used to treat schizophrenia in patients who have not been helped by or are unable to take other medicines.

Clozapine is available only from pharmacies that agree to participate with your doctor in a plan to monitor your blood tests. You will need to have blood tests done every week for at least 6 months. After that, your doctor will decide if it is safe for you to have blood tests every other week. You will receive enough clozapine to last until your next blood test, but only if the results of your blood tests show that it is safe for you to take this medicine. If any of your blood tests are not normal, you may need to have blood tests more often than every week until they return to normal.



Clozapine is available in the following dosage form:
Oral
Tablets (U.S. and Canada)
Before Using This Medicine</H3>In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For clozapine, the following should be considered:



Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to clozapine. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy—Clozapine has not been studied in pregnant women. However, clozapine has not been shown to cause birth defects or other problems in animal studies.

Breast-feeding—Clozapine may pass into breast milk and cause drowsiness, trouble in nursing, restlessness or irritability, convulsions (seizures), or heart or blood vessel problems in nursing babies.

Children—Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of clozapine in children with use in other age groups.

Older adults—Many medicines have not been tested in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Clozapine may be more likely to cause side effects in the elderly, including dizziness and fainting, low blood pressure, and confusion or excitement.

Other medicines—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking clozapine, it is especially important that your health care professional know if you are taking any of the following:
Alcohol or
Central nervous system (CNS) depressants (medicines that cause drowsiness) or
Tricyclic antidepressants (amitriptyline [e.g., Elavil], amoxapine [e.g., Asendin], clomipramine [e.g., Anafranil], desipramine [e.g., Pertofrane], doxepin [e.g., Sinequan], imipramine [e.g., Tofranil], nortriptyline [e.g., Aventyl], protriptyline [e.g., Vivactil], trimipramine [e.g., Surmontil])—Using these medicines or alcohol with clozapine may cause increased drowsiness, low blood pressure, or trouble in breathing
Amantadine (e.g., Symmetrel) or
Antihypertensives (high blood pressure medicine) or
Antipsychotics (medicine for mental illness) or
Bromocriptine (e.g., Parlodel) or
Certain eye drops used to treat glaucoma (carteolol [e.g., Ocupress], levobunolol [e.g., Betagan], metipranolol [e.g., OptiPranolol], timolol [e.g., Timoptic]) or
Diuretics (water pills) or
Levodopa (e.g., Dopar) or
Medicine for heart disease or
Nabilone (e.g., Cesamet) (with high doses) or
Narcotic pain medicine or
Pentamidine (e.g., Pentam) or
Pimozide (e.g., Orap) or
Promethazine (e.g., Phenergan) or
Trimeprazine (e.g., Temaril)—Using these medicines with clozapine may cause low blood pressure, which can cause dizziness or fainting
Amphotericin B by injection (e.g., Fungizone) or
Antineoplastics (cancer medicine) or
Antithyroid agents (medicine for overactive thyroid) or
Azathioprine (e.g., Imuran) or
Chlorambucil (e.g., Leukeran) or
Chloramphenicol (e.g., Chloromycetin) or
Colchicine or
Cyclophosphamide (e.g., Cytoxan) or
Flucytosine (e.g., Ancobon) or
Ganciclovir (e.g., Cytovene) or
Interferon (e.g., Intron A, Roferon-A) or
Mercaptopurine (e.g., Purinethol) or
Methotrexate (e.g., Mexate) or
Plicamycin (e.g., Mithracin) or
Zidovudine (e.g., AZT, Retrovir)—Taking clozapine with any of these medicines may increase the chance that very serious blood problems will occur
Lithium—Using clozapine with lithium may increase the chance that convulsions (seizures), confusion or problems with movement will occur
Selective serotonin reuptake inhibitors (fluoxetine [e.g., Prozac], fluvoxamine [e.g., Luvox], paroxetine [e.g., Paxil], sertraline [e.g., Zoloft])—These medicines can increase the blood levels of clozapine, which increases the chance that unwanted effects will occur
Other medical problems—The presence of other medical problems may affect the use of clozapine. Make sure you tell your doctor if you have any other medical problems, especially:
Blood diseases or
Enlarged prostate or difficult urination or
Gastrointestinal problems or
Glaucoma, narrow angle or
Heart or blood vessel problems—Clozapine may make these conditions worse
Epilepsy or other seizure disorder—Clozapine may increase the chance that seizures will occur
Kidney or liver disease—Higher blood levels of clozapine may occur, increasing the chance that unwanted effects will occur
Take this medicine exactly as directed . Do not take more of this medicine and do not take it more often than your doctor ordered. Do not miss any doses.

This medicine has been prescribed for your current medical problem only . It must not be given to other people or used for other problems unless you are directed to do so by your doctor.



Dosing—The dose of clozapine will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of clozapine. If your dose is different, do not change it unless your doctor tells you to do so.

The number of tablets that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on your special needs .
For oral dosage form (tablets):
For schizophrenia:
Adults—At first, 12.5 milligrams (mg) (one half of a 25-mg tablet) once or twice a day. Your doctor may increase your dose as needed. However, the dose usually is not more than 900 mg a day.
Children younger than 16 years of age—Use and dose must be determined by your doctor.


Missed dose—If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. If you miss 2 or more days of clozapine doses, talk to your doctor before you start taking it again. You may need to restart this medicine at a lower dose than you were taking before.

#4 Adnan

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Posted 23 May 2006 - 20:40

ja sam se time drogiro jedno vrijeme popijem veliki onaj jedan toliko me derne da jedva stojim a i jedva pricam

#5 pokisla

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Posted 23 May 2006 - 21:33

e jebote adnane ti nisi normalan.

#6 Sendy

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Posted 02 June 2006 - 16:42

View PostAdnan, on 23 May 2006, 09:40 PM, said:

ja sam se time drogiro jedno vrijeme popijem veliki onaj jedan toliko me derne da jedva stojim a i jedva pricam
:meda: xaxaxaxa! E da mi je samo znati koji si ti alien i s koje si planete? Keve mi si lik! :haha:

#7 Adnan

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Posted 03 June 2006 - 00:28

jeben pravo do leci

#8 Sendy

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Posted 03 June 2006 - 13:20

View PostAdnan, on 3 Jun 2006, 01:28 AM, said:

jeben pravo do leci
:meda: ??????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????
?????????????????????????????????????????????????????
?????????????????????????????????????????'
?????????????????????

#9 Stepska Vucica

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Posted 21 October 2006 - 22:46

Mojoj sestri su prosle godine dijagnostikovali psihozu. Bar su tako lekari mislili. Lecili su je sa par vrsta lekova i razlicitim dozama, ali ona odbija da ih pije jer se plasi da ce se udebljati ( i sada pati od simptoma anoreksije, koju "vuce" od detinjstva ).
Nakon godinu dana manje-vise bezuspesnog lecenja ( sa periodima poboljsanja i pogorsanja ), lekari su odlucili da predju na CLOZAPINE. Moja sestra me je pre neki dan zvala i sva uspanicena mi rekla kako misli da lekari hoce da eksperimentisu taj lek na njoj i da hoce da je ubiju jer su joj rekli da ima veoma opasna nezeljena dejstva na srce! Kada sam proverila preko interneta, ispalo je da je puno toga poznato o tom leku - zasto bi ga naknadno testirali na ljudima, i to bas na njoj? I takodje to da se daje onima koji boluju od shizofrenije koja ne reaguje na bar druga dva leka slicnog dejstva ...
Da li to znaci da su joj posle toliko vremena dijagnostikovali shizofreniju, i to oblik tezak za lecenje? To pitam jer ne znam detalje u vezi sa njom i njenom dijagnozom posto sada zivimo u razlicitim zemljama, a ona se naprasno razbolela nakon odlaska u inostranstvo ...

Unapred hvala na odgovorima ...

#10 dRiFtEr

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Posted 21 October 2006 - 23:23

to je antipsihotik druge generacije.
izme?u ostalog koristi se i za lije?enje shizofrenije,makar je danas zyprexa(olanzapin) preuzeo glavnu ulogu.
najizraženije nuspojave clozapina su sedacija i pove?anje tjelesne težine.

#11 danica

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Posted 22 October 2006 - 07:32

Koliko shvatam njenu situaciju, to su joj dali jer nije reagovala na druge antipsihotike. Ocigledno joj nije pomogao ni rispolept, ni ostali lekovi. S obzirom da joj simptomi traju veoma dugo (mislim da je vise od godine) verovatno su joj i postavili tu dijagnozu.
Sta kaze zet? Nisam se cula sa njim vec par nedelja.

#12 Stepska Vucica

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Posted 22 October 2006 - 14:06

Nemam sveze informacije odande ...

E sad, veliko je pitanje da li ti lekovi koje je pila zaista nisu delovali, ili ih ona nije uzimala redovno kada nije kontrolisana ( ili je lagala da ih je pila, a nije ), posto i dalje ima panican strah od debljanja, umesto da se orijentise na to da joj bude bolje ... Njoj je "dobra linija" ( bolje receno, mrsavost ) bitnija od psihickog zdravlja i zdravlja uopste ...

:clapping:

I dalje nece da saradjuje sa lekarima i krije koliko god moze ponovne pojave deluzija, a kada vec postanu svima ocigledne, tada je teze za reagovanje i terapiju ...

Ima li neko ideju sa uraditi sa ovakvim karakterom, sa osobom koja uporno odbija sve pokusaje izlecenja ili bar zalecenja?

#13 dRiFtEr

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Posted 22 October 2006 - 14:18

prisilno lije?enje za njeno dobro.ona je u stanju bježati od problema kolko god treba i nebude svojevoljno pristala na lije?enje nikada.još k tome mi se ?ini, iz ovoga što si napisala, da ju je pojela i paranoja.

#14 Stepska Vucica

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Posted 22 October 2006 - 14:35

Da, upravo tako, nepodnosljivo je paranoicna i to ispoljava mnogobrojnim umisljenim "zakljuchcima" i paranoicnim stavovima!

#15 dRiFtEr

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Posted 22 October 2006 - 14:47

nema tu više manevarskog prostora.nekad u životu do?e vrijeme kada se moraju raditi radikalni potezi,kolko god bili nepopularni. o?ito više nije u stanju kada može racionalno donosit odluke za svoju dobrobit. sad je red na obitelji da ju zaštiti od bolesti ali i od same sebe. jednog dana ?e vam biti zahvalna.

#16 danica

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Posted 22 October 2006 - 15:50

Ako se dobro secam pila je ona lekove, samo u veoma malim kolicionama (s obzirom na jacinu simptoma i vrstu bolesti) zato sto je imala jaka nezeljena dejstva. Ako se secas da sam se cudila kako mogu da joj u akutnoj psihoticnoj fazi daju npr. samo 2mg rispolepta.
Ako se sumnja da uopste pije lekove treba zet da joj daje. A to da svi antipsihotici goje je definitivno. Pitanje je i to da li je ona uopste shvatila tezinu svog stanja. Cini mi se da mi je D rekao da nije nikad sastavila ni mesec dana bez simptoma.

#17 Stepska Vucica

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Posted 22 October 2006 - 19:02

Da, Danice, sve to stoji: i jaka nezeljena dejstva cak i malih doza, i ceste remisije ( ili kako se vec zove ponovno pojavljivanje simptoma ) i ostalo sto si pobrojala. Medjutim, pitam se sta ce sada sa njom raditi, kada u Kanadi ( gde je ona ) pod prisilom lece samo one pacijente koji su pokusali suicid ( a i to je probala ), pa cak ni to ne vise od mesec dana u bolnici. Za sve pitaju i uvazavaju misljenje samog pacijenta, pa cak i kada on ili ona ocigledno nije u stanju da shvati tezinu sopstvene bolesti i radi na svoju stetu! To je neshvatljiva primena zapadne demokratije cak i u domenu psihijatrije.
Jos jedna otezavajuca okolnost je to sto ona tamo nema nikoga od familije, osim svog supruga, kome je i ovako tesko da se bori sa svim tim ... Ovo su bile napomene i za ostale; mozda neko moze da da neki pametan savet.
Kada smo se cule pre neki dan, napomenula je da je u poslednje vreme pila 800 mg Seroquela i tvrdi da joj je bilo bolje sa tom dozom i tom vrstom leka. Ipak, mora da postoji neki valjan razlog zbog koga su resili da opet promene terapiju ... a ona je to propratila jos jednom jakom paranoidnom reakcijom.

#18 Stepska Vucica

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Posted 23 October 2006 - 23:39

Ja zaista ne znam sta da radimo sa mojom sestrom ... Upravo sam saznala kako je rekla da bi radije bila psihicki bolesna, nego da se udeblja zbog koriscenja antipsihotika i drugih lekova ... Ona konstantno odbija saradnju s alekarima i cak je vrlo neprijatna prema njima. Oni, verujem, ni sami ne znaju kako da izadju na kraj sa njom ... Pa jos ta njihov blesava klauzula, pravilo ili sta god da je - da nikoga ne lece silom ako sam to ne zeli, to ce je unistiti do kraja ...

#19 danica

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Posted 24 October 2006 - 06:16

Nek proba zet da je uceni.

#20 Stepska Vucica

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Posted 24 October 2006 - 11:32

Uh, ne znam da li bi ucena uspela, jer ona i ovako vec pravi nepodnosljive scene na sasvim bezazlene stvari, i zapravo je ona ta koja ucenjuje ... Ne vidim drugog resenja osim to da je silom odvedu u bolnicu i na silu lece, ali oni takve stvari, na zalost, u Kanadi ne rade ...

Ima li neko jos neki predlog kada resiti ovaj teeeeeezak problem?


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