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deficitarna i nedeficitarna šizofrenija


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#1 WANNABE

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Posted 05 May 2017 - 15:51

zanimljivo za čitanje nisam znao da ima i ova podela

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Deficit schizophrenia: an update



The criteria for deficit schizophrenia were designed to define a group of patients with enduring, primary (or idiopathic) negative symptoms. In 2001, a review of the literature suggested that deficit schizophrenia constitutes a disease separate from nondeficit forms of schizophrenia. Here we provide a review of new studies, not included in that paper, in which patients with deficit schizophrenia and those with nondeficit schizophrenia were compared on dimensions typically used to distinguish diseases: signs and symptoms, course of illness, pathophysiological correlates, risk and etiological factors, and treatment response. Replicated findings and new evidence of double dissociation supporting the separate disease hypothesis are highlighted. Weaknesses in research and treatment options for these patients are also emphasized.
Keywords: Deficit schizophrenia, heterogeneity, negative symptoms, apathy, double dissociation

Deficit schizophrenia is a syndrome defined by the following criteria: a) presence of at least two out of six negative symptoms: restricted affect (referring to observed behaviours rather than to the patient's subjective experience); diminished emotional range (i.e., reduced range of the patient's subjective emotional experience); poverty of speech; curbing of interests; diminished sense of purpose; diminished social drive; b) some combination of two or more of the above symptoms have been present for the preceding 12 months and were always present during periods of clinical stability; c) the above symptoms are primary or idiopathic, i.e., not secondary to factors such as anxiety, drug effect, psychotic symptoms, mental retardation, depression; d) the patient meets DSM criteria for schizophrenia 1-3.


a onda ovo




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Neurocognitive impairment in deficit and non-deficit schizophrenia: a meta-analysis.



BACKGROUND:

Most studies suggested that patients with deficit schizophrenia have more severe impairment compared with patients with non-deficit schizophrenia. However, it is not clear whether deficit and non-deficit schizophrenia are associated with differential neurocognitive profiles.
METHODS:

The aim of this meta-analytic review was to compare cognitive performances of deficit and non-deficit patients with each other and with healthy controls. In the current meta-analysis, differences in cognitive abilities between 897 deficit and 1636 non-deficit patients with schizophrenia were examined. Cognitive performances of 899 healthy controls were also compared with 350 patients with deficit and 592 non-deficit schizophrenia.
RESULTS:

Both deficit (d = 1.04-1.53) and non-deficit (d = 0.68-1.19) schizophrenia were associated with significant deficits in all cognitive domains. Deficit patients underperformed non-deficit patients in all cognitive domains (d = 0.24-0.84) and individual tasks (d = 0.39-0.93). The relationship between deficit syndrome and impairment in olfaction, social cognition, verbal fluency, and speed-based cognitive tasks were relatively stronger.
CONCLUSIONS:

Our findings suggest that there is consistent evidence for a significant relationship between deficit syndrome and more severe cognitive impairment in schizophrenia.



#2 tirkiz

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Posted 06 May 2017 - 21:48

dva puta sam procitala ali nisam bas najbolje razumela.msm, sta sad, doneli zakljucak i sta dalje? i razmisljam, ako ima vec toliko podela, zasto se medicina ne potrudi malo vise da tako ciljano prave i lekove?
hmmm,
u stvari me rastuzuje cinjenica da sto god procitam uvek nekako ostane da visi u vazduhu jos samo malo, jos samo malo... i pri tom mislim na sve bolesti, a pogotovo na bolesti duse...kao nauka jos nije dala odgovor, kao nista to nije eksplicitno, jos je neistrazeno, jos se ne zna...

#3 WANNABE

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Posted 07 May 2017 - 11:41

ima nekoliko lekova za negativne i kognitivne simptome koji su u fazi testiranja
i ako prođu testiranja do nas će to stići za otprilike 10 godina

#4 kicavac

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Posted 18 October 2017 - 22:08

Koji je najtezi oblik sizofrenije?

#5 WANNABE

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Posted 18 October 2017 - 22:11

ja bih rekao katatonična
hebefrena je lakši oblik a paranoidna najlakši

#6 Hyperdrive

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Posted 18 October 2017 - 22:13

Sad se ja pitam šta ima moja rođaka. Ona nema pojma ko je ko, priča u tri različita glasa i ponavlja neke čudne stvari vezane za svog oca, koje zvuče kao neki izveštaj o njegovoj smrti.

#7 kicavac

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Posted 18 October 2017 - 22:37

Katatona je retka. Moguce da je hebefrena foggy. Dr je spomenuo za brata da ima najtezi obl8k sizofrenije ali nije katatona. Ne znam na sta je mislio.

#8 Hyperdrive

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Posted 18 October 2017 - 22:48

Sad sam pogledala simptome i mislim da si u pravu. :( Majko mila, ovo je strašno!

#9 archaic_tiger

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Posted 19 October 2017 - 10:49

Foggy,a zar ne postoji neko od familije (rodbina,rođaci i sl) ko bi već znao da ti kaže koju tačno psihijatrijsku dijagnozu ima ta tvoja rođaka? Jer ovako preko Foruma je to zaista teško reći...

Ili ti je iz nekog razloga neprijatno da ih to pitaš (i uopšte,da potežeš tu temu)?

#10 Hyperdrive

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Posted 19 October 2017 - 11:53

Stvar je komplikovana.

Mi smo joj jedina živa rodbina. Ona je u provinciji, pod nadležnošću centra za socijalni rad, od kako joj je 2011. umrla majka. Socijalno nas nije obavestilo o smrti njene majke. Bile smo tamo par puta, sad nemamo kinte da odemo. Paket se vratio, sad idem po njega.

Negde, ali negde imamo par izveštaja lekara iz bolnice u Požarevcu, ali dobile smo ih u vreme kad ja nisam znala sve F-ove napamet, i sad ne znamo gde su.

Mama će sutra zvati socijalno (stalno odlaže, mislim da se plaši odgovora) i videćemo šta se dešava. Plašimo se da je nisu smestili negde, zauvek.

Izvinjavam se što sam ukrala temu.

#11 WANNABE

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Posted 29 June 2018 - 10:07

 WANNABE, on 18 October 2017 - 22:11 , said:

ja bih rekao katatonična
hebefrena je lakši oblik a paranoidna najlakši

hmm nedavno sam naisao na podatak da se katatonicna uspesno tretira lekovima danas
pa se mozda zbog toga ne bi moglo reci da je najteza

ostaju hebefrenija i sizofrenija simplex kao bas teske

paranoidna mi i dalje deluje najlaksa iako mozda najvise sranja sebi i drugima naprave bas paranoidni sizofrenicari

ma ne znam u stvari
svaka sizforenija je pakao

#12 Iimitless

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Posted 29 June 2018 - 18:16

Zar nije bila neka prica da ce ukinuti podele sizofrenije i posmatrati je kao neki spektar?

#13 WANNABE

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Posted 29 June 2018 - 18:23

mislim da su to amerikanci vec uradili

#14 Hyperdrive

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Posted 30 June 2018 - 00:03

Ako sam dobro shvatila, SHPD i onaj drugi su deo tog spektra.

#15 Iimitless

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Posted 30 June 2018 - 00:29

 Hyperdrive, on 30 June 2018 - 00:03 , said:

Ako sam dobro shvatila, SHPD i onaj drugi su deo tog spektra.

Mislis sizoidni i sizotipalni pl?

#16 Hyperdrive

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Posted 30 June 2018 - 21:55

Ne, ono treće. Schizofreniform (?).

Znam da shizoidni ne ide u tu grupu.


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