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osobe sa šizofrenijom ubrzano stare u kognitivnom smislu


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#1 ĐeneĐene

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Posted 17 May 2017 - 21:48

Cognitive and functional deficits in people with schizophrenia: Evidence for accelerated or exaggerated aging?


Cognitive and functional deficits are commonly seen in people with schizophrenia. The profile of these impairments has a resemblance to the cognitive changes seen in healthy aging. In specific, many of the cognitive ability domains that change the most with aging in healthy people are the most salient of these deficits seen in people with schizophrenia, including prominent deficits in processing speed, working memory, and episodic memory. Functional deficits seen in schizophrenia are also similar to those seen in healthy aging. There is a relationship between multiple psychotic relapses and treatment resistance and longitudinal cognitive and functional changes in schizophrenia, with this relationship starting early in the course of illness. Cognitive performance in people with schizophrenia may be consistent with accelerated or premature aging. People with schizophrenia perform similarly to healthy people who are 3 or more decades older on indices of both cognition and their everyday functional skills. Some people with schizophrenia show exaggerated cognitive changes as well. Cognitive and functional performance worsens at the outset of the illness in schizophrenia compared to premorbid functioning, meaning that these deficits are not due to development disabilities. There are multiple medical and substance abuse comorbidities in schizophrenia and although these comorbidities affect cognitive functioning, they are not completely responsible for age-related changes.

#2 ĐeneĐene

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Posted 17 May 2017 - 21:50

ako imam šizu ovo bi mnogo stvari objasnilo...

#3 VanjaCro

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Posted 17 May 2017 - 22:23

pa zar nisu kognitivni simptomi upravo oni koji i djeluju na memoriju itd... ?
smetnje u pamcenju etc....
to je opce poznato da je tako ne samo kod shizofrenije

#4 ĐeneĐene

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Posted 17 May 2017 - 23:00

šta je opšte poznato nisam te razumeo?

hoće i kod drugih oboljenja da se jave kognitivni problemi to je tačno
ali pitanje je koliko su kvalitativno i kvantitativno izraženi kada se uporede sa kognitivnim korpusom šizofrenih simptoma
plus što su u šizofreniji oni trajni i ne nestaju sa povlačenjem bolesti

#5 VanjaCro

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Posted 17 May 2017 - 23:20

View Post2Bavailable, on 17 May 2017 - 23:00 , said:

šta je opšte poznato nisam te razumeo?

hoće i kod drugih oboljenja da se jave kognitivni problemi to je tačno
ali pitanje je koliko su kvalitativno i kvantitativno izraženi kada se uporede sa kognitivnim korpusom šizofrenih simptoma
plus što su u šizofreniji oni trajni i ne nestaju sa povlačenjem bolesti
ma mislim pod kognitivne da se odnose na smetnje u pamcenju, koncentraciji itd... pa rekoh "opce poznato"
ma shizofrenija je pakao na zemlji
a ovo sa starenjem u smislu kognitivnih funkcija ima logike
tamo gdje bolest napada taj dio moze samo jos vise propadati na zalost
jedina pozitivna stvar je ta sto se ne gubi inteligencija ali vjerujem da razori tako jako da se netko sa tom bolesti cini drugima kao da je malouman
no zapravo nije naravno
nebi najgorem protivniku tu bolest koliko je zapravo odvratna kad bolje promislis o njoj

#6 ĐeneĐene

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Posted 17 May 2017 - 23:38

da jasno...
iskreno ne znam ni šta sve spada u te kognitivne simptome

ima ovo u depresiji
  • Negative or distorted thinking
  • Difficulty concentrating
  • Distractibility
  • Forgetfulness
  • Reduced reaction time
  • Memory loss
  • Indecisiveness
u šizi je
  • disorganized thinking
  • slow thinking
  • difficulty understanding
  • poor concentration
  • poor memory
  • difficulty expressing thoughts
  • difficulty integrating thoughts, feelings and behavior


#7 VanjaCro

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Posted 18 May 2017 - 00:10

View Post2Bavailable, on 17 May 2017 - 23:38 , said:

da jasno...
iskreno ne znam ni šta sve spada u te kognitivne simptome

ima ovo u depresiji
  • Negative or distorted thinking
  • Difficulty concentrating
  • Distractibility
  • Forgetfulness
  • Reduced reaction time
  • Memory loss
  • Indecisiveness
u šizi je
  • disorganized thinking
  • slow thinking
  • difficulty understanding
  • poor concentration
  • poor memory
  • difficulty expressing thoughts
  • difficulty integrating thoughts, feelings and behavior
pa koliko se sjecam to su kognitivni simptomi
poteskoce sa pamcenjem, ucenjem, neshvacanjem drugih sta ti govore ponekad, nemos pratiti vise stvari odjednom itd....
sve to sto je navedeno bi se moglo strpati pod to makar mislim

najveci pakao svega toga je sto neke situacije ili ljude koje osoba sa shizofrenijom "dozivi" ili "prozivi" zapravo nikada nisu bile stvarne situacije a niti stvarni ljudi
zamisli taj pakao kad netko shvati da takve situacije nikada nisu niti postojale (ako ikada shvati)
vjerujem da je tako sta u najtezim oblicima te bolesti i da je to zapravo najgori dio svega
fuj
ali stvarno nemam rijeci za tu bolest

#8 aspire

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Posted 18 May 2017 - 15:35

Točno je, ali uz odgovarajuću terapiju razlika u odnosu na zdrave ljude se može svesti na minimum. Ne baš kod svih, ali kod 90% ljudi sa šizom je tako.

#9 VanjaCro

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Posted 18 May 2017 - 15:54

View Postaspire, on 18 May 2017 - 15:35 , said:

Točno je, ali uz odgovarajuću terapiju razlika u odnosu na zdrave ljude se može svesti na minimum. Ne baš kod svih, ali kod 90% ljudi sa šizom je tako.
to definitivno
ali ovisi od osobe do osobe i koju vrstu shize ima
inace paranoidni najbolje i prolaze nekako

#10 ĐeneĐene

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Posted 18 May 2017 - 18:02

aha i meni se čini da paranoidna ima najmanje deficita
pa onda dezorganizovana
pa onda katatonična koju ne bih ni hitleru poželeo

#11 ĐeneĐene

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Posted 18 May 2017 - 18:08

View Postaspire, on 18 May 2017 - 15:35 , said:

Točno je, ali uz odgovarajuću terapiju razlika u odnosu na zdrave ljude se može svesti na minimum. Ne baš kod svih, ali kod 90% ljudi sa šizom je tako.

nije baš 90% jer se nekih 50% oporavi dovoljno da može samostalno da funkcioniše
baš sam kačio neki dan tu statistiku sad ću da iskopam

#12 ĐeneĐene

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Posted 02 August 2017 - 07:17

https://www.ncbi.nlm...pubmed/28740828

Omega-3 fatty acids related to cognitive impairment in patients with schizophrenia.



Cognitive impairment is strongly associated with functional outcome in patients with schizophrenia but its pathophysiology remains largely unclear. Involvement of omega-3 fatty acids in the cognitive function of healthy individuals and patients with neuropsychiatric disease has received increasing attention. The aim of this study was to examine the relationship between omega-3 fatty acids with cognitive function, social function, and psychiatric symptoms in patients with schizophrenia. The subjects included 30 patients with schizophrenia or schizoaffective disorder. Psychiatric symptoms, cognitive function, and social function were assessed using the Positive and Negative Syndrome Scale, the Brief Assessment of Cognition in Schizophrenia (BACS), and the Social Functioning Scale (SFS), respectively. Blood serum omega-3 fatty acids were assessed using gas chromatography. The BACS composite score was significantly correlated with blood eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) levels. In addition, a daily dose of antipsychotic medication was negatively and significantly correlated with the blood DHA level and with the BACS composite score. Step-wise multiple regression analyses demonstrated that the SFS score was significantly associated with the BACS composite score. Our results indicate that reduced blood omega-3 fatty acids are associated with cognitive impairment, which then impacts social functioning outcomes in schizophrenia.


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